Thomas M.S. Chang, is a physician and scientist.
In 1957, while an undergraduate at McGill University he invented the world's first artificial cell. Working with improvised materials like perfume atomizers inside his dorm room turned laboratory, Chang managed to create a permeable plastic sack that would effectively carry almost as effectively as a natural . He went on to complete his , , and degrees at McGill. Chang's career continued as Director of the Artificial Cells and Organs Research Centre and Professor of Physiology, Medicine & Biomedical Engineering in the at McGill University.
In the late sixties he discovered enzymes carried by artificial cells could correct some metabolic disorders and also developed charcoal-filled cells to treat drug poisoning. His work on finding a safe blood substitute brought him to prominence in the 1980s and 1990s, earning him an Order of Canada.